Blar i forfatter "Alexopoulou, Eirini"
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Fibroblast in vitro stimulation with TGFβ1 and bFGF; αSMA expression and S100A4 immunohistochemistry staining in oral cancer
Alexopoulou, Eirini (Master thesis; Mastergradsoppgave, 2020-12-16)Oral squamous cell carcinoma (OSCC) is an aggressive cancer associated with high mortality rates. The objective of this master project was to test the following hypotheses: (1) transforming growth factor β1 (TGFβ1) activates fibroblasts in vitro and basic fibroblast growth factor (bFGF) deactivates them while both increase fibroblast proliferation in cancer associated fibroblasts (CAFs); (2) the ...